ABC Primetime Investigative Report…and update

1,000,000x Stronger Than Dietary Antioxidants Like Vitamin C!*


Used for 4,000 years in both Ayurvedic and Chinese cultures and shown to help fight cellular stress, maintain joint health, and aid digestion.*


Contains high concentration of powerful antioxidants and known to support healthy mental processes and cardiovascular health.*


Known to promote cognitive abilities, concentration, and alertness, and studies suggest it provides strong cellular defense.*


Used for 2,000 years to support liver, kidney, and gallbladder function, and studies suggest it supports healthy detoxification.*


The “king of Ayurvedic herbs,” an adaptogen with multiple benefits, including support for memory enhancement and restful sleep.*

Studies on Protandim NRF2 Synergizer® have been published and peer-reviewed from some of the world’s most respected research institutions, including:

University of Colorado
Denver Health Medical Center
Children’s Hospital, Denver
Virginia Commonwealth University
Colorado State University
University of Florida
University of Kentucky

University of Michigan
Louisiana State University
Ohio State University
Harvard University
Vanderbilt University
Northwestern, University
National Institute of Aging

Glamorgan University, Wales
Sahlgrenska Uni. Hospital, Sweden
University of Montreal, Quebec
University Hospital, Brno, Czech Republic
Mexican Institute of Social Security, Mexico
VU Uni. Medical Center, Neuroscience Campus
Amsterdam, The Netherlands

To search the connection of oxidative stress to any health concern, simply go to and type in “Oxidative Stress + Health Issue” (ie: Oxidative Stress Cancer, Oxidative Stress Diabetes) etc. 

Click on the buttons below to go directly to and view studies on Oxidative Stress, Protandim NRF2 and NRF2

Conclusions of Protandim and NRF2 Technology:

University of Texas, 2010
“Nrf2 is a guardian of healthspan and the gatekeeper of species longevity…protecting against many age related diseases including cancer and neurodegeneration.”

Washington State University, 2015
“Nrf2 is likely to be the most important health promoting approach in the foreseeable future. Nrf2 may become the most extraordinary therapeutic and preventative breakthrough in the history of medicine.”

Louisiana State University, 2009
“Induction of antioxidant enzymes by Protandim® may serve as a practical and potent approach to cancer prevention.”

National Institute of Aging, 2017
“Protandim® is the only nutritional supplement tested that has been proven to increase the median survival in mice, thus delaying the aging process. It has the potential to extend lifespan.”

US Patent 7,241,461

Compositions for alleviating inflammation and oxidative stress in a mammal.

US Patent 7,384,655

Preparation of compositions to alleviate inflammation and oxidative stress in a mammal

US Patent 7,579,026

Methods for enhancing antioxidant enzyme activity and reducing c-reactive protein levels.

US Patent 7,923,045

Compositions for alleviating inflammation and oxidative stress in a mammal

US Patent 8,221,805

Compositions for alleviating inflammation and oxidative stress in a mammal.

US Patent 8,435,574

Preparation of compositions to alleviate inflammation and oxidative stress in a mammal

US Patent 9,265,808

Compositions for alleviating inflammation and oxidative stress in a mammal

CHASING LIFE by Dr. Sanjay Gupta

This anti-aging best-seller highlights Dr. Joe McCord’s 40 years of breakthroughs in medicine, along with his research and formulation of Protandim NRF2.

Quoting the book “Superoxide Dismutase (SOD)…and catalase. Two enzymes, he (Dr McCord) says, are responsible for scavenging 99% of the free radicals in the body. If we can get the body to produce more of these enzymes, he reasons, then it would do a better job at fighting free radicals.

McCord recently coauthored an article in the journal of Free Radical Biology and Medicine and showed how a supplement containing five such plant extracts (Protandim NRF2) not only increase the body’s production of SOD and catalase but decrease the markers for oxidative stress associated with aging.”

Real People. Real Results.

Read what a handful of happy users are saying about what an activated life has done for them.

I stopped going to the chiropractor after biweekly appointments for 20 years!

Jason G.

After starting NRF2, I have a lot less stiffness. I feel I have better sleep, and noticing better skin and hair… and my blood pressure is in a healthy range.


My brain fog is gone! I sleep soundly and wake up refressed. I look and feel better at 48 than I did at 38 (actually got recently ID’d haha!)

Candace F.

My joints are way more comfortable. I sleep like a baby and wake up with amazing energy!

Clint G.

NRF2 Activation FAQ

What is Protandim NRF2 Synergizer?

Protandim Nrf2 Synergizer is the only supplement proven in a peer- reviewed, human clinical study to reduce cellular stress in humans by an average of 40 percent in 30 days. Protandim Nrf2 Synergizer is patent protected and is the subject of 20 peer-reviewed clinical studies.

Protandim Nrf2 Synergizer works to support the body’s own protective measures by turning on its internal antioxidant defense system, regulated by the protein Nrf2. When activated, Nrf2 triggers cells to produce naturally occurring antioxidant enzymes as well as housekeeping “cleanup” proteins which work together to deliver balanced protection against cellular stress.

Are the raw ingredients tested/manufactured?

Yes, the Quality Control measures implemented by LifeVantage go beyond industry standard. LifeVantage rigorously tests every lot of active raw material for identity, potency, microbial contamination, pesticides and heavy metals. Unlike most dietary supplement companies, we also physically audit all of our active raw material suppliers. We perform exhaustive testing to verify that all materials meet or exceed quality specifications.

The raw ingredients are verified, carefully weighed out, blended and pressed into tablet form following strict Good Manufacturing Practices (GMP) guidelines.

Every lot of finished Protandim Nrf2 Synergizer is tested for compliance to approved specifications in addition to receiving a final quality inspection following dietary supplement regulations. Every lot must, again, meet or exceed established finished product specifications before it can be released by LifeVantage Quality Assurance.

What is the NSF certification that Protandim NRF2 has?

Certification by NSF means that an independent organization has reviewed the manufacturing process of a product and determined that the final product complies with specific standards for safety, quality or performance. NSF certification is recognized by regulatory agencies at the local, state, federal and international level, and NSF periodically conducts audits and product testing to verify that the product continues to comply with the standard.

I eat vegetables and fruits and take antioxidant supplements. Why do I need Protandim NRF2?

Many people mistakenly believe their antioxidant needs are fulfilled by eating blueberries, drinking expensive “miracle juices” and applying antioxidant facial creams.

What they don’t realize is that their daily antioxidant needs cannot be fulfilled by consuming any amount (or even buckets full) of blueberries, kale, broccoli, acai juice, vitamin C tablets, dark chocolate or red wine.

Effective antioxidant protection absolutely requires adequate production of the body’s own antioxidant enzymes. Protandim Nrf2 Synergizer contains a unique, patented blend of ingredients that have been proven to stimulate the production of antioxidant enzymes and protect against cellular stress.

When/how should I take Protandim NRF2?

Some of the active ingredients in Protandim Nrf2 Synergizer are fat soluble, so taking Protandim Nrf2 Synergizer with a meal containing some fat allows the ingredients to be absorbed more efficiently (but it’s not absolutely necessary). Most people choose to take it in th emorning, but it can be taken at any time of day.

PROPER DISCLOSURES: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

The Distributor sales earnings disclosed are potential gross earnings and not net of other business expenses and not necessarily representative of the actual income, if any, that a Distributor can or will earn through the LifeVantage Sales Compensation Plan. A Distributor’s earnings will depend on individual diligence, work effort and market conditions. LifeVantage does not guarantee any income or rank success.

See the Average Annual Earnings Disclosure for detailed earnings information per rank.

This website is owned and operated by Independent LifeVantage Distributors.